The hosts lead 1-0 after winning a rain-hit match reduced to seven overs a side in Brisbane on Thursday by 29 runs.
Australia are again without several top players — who are preparing for the Test series against India which begins next week — and named an unchanged side.
Pakistan, who won the preceding one-day series 2-1, made one change, with wrist spinner Sufiyan Muqeem replacing Haseebullah Khan
Teams
Australia: Jake Fraser-McGurk, Matt Short, Josh Inglis (capt), Glenn Maxwell, Marcus Stoinis, Tim David, Aaron Hardie, Xavier Bartlett, Nathan Ellis, Adam Zampa, Spencer Johnson
Pakistan: Sahibzada Farhan, Mohammad Rizwan(capt), Babar Azam, Usman Khan, Agha Salman, Irfan Khan, Abbas Afridi, Shaheen Afridi, Naseem Shah, Haris Rauf, Sufiyan Muqeem
