College football Week 4 live updates: NC State at Clemson, USC at Michigan and more

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Week 4 of the college football season features the start of conference play for many teams, and it includes two games between teams ranked in the top 15. Both of those matchups could prove to be crucial at the end of the season.

Here are the biggest games on Saturday.

(All times are Eastern and all odds are from BetMGM.)

Time: Noon | TV: ABC | Line: Clemson -20.5 | Total: 47

Clemson is 1-1 with an ugly loss to Georgia and a blowout win over Appalachian State in Week 2. NC State is also dealing with a rough start to its season with a narrow win over Western Carolina and a blowout loss to Tennessee. Wolfpack QB Grayson McCall will miss Saturday’s game with an injury.

Time: 3:30 p.m. | TV: CBS | Line: USC -6 | Total: 44.5

Michigan will start Alex Orji at quarterback against the Trojans after Davis Warren started the first three games and was mostly ineffective. The Wolverines will likely employ a run-heavy attack that will test a USC defense that suddenly looks very feisty.

Time: 4 p.m. | TV: Fox | Line: Oklahoma State -2.5 | Total: 52.5

After missing Utah’s Week 3 win over Utah State, all signs point to Cameron Rising playing against the Cowboys. And that’s big news for this game that could go a long way in determining the top of the Big 12 standings. The Cowboys are favored at home after the line had Utah as a small favorite earlier in the week.

Time: 7:30 p.m. | TV: ABC | Line: Tennessee -7 | Total: 57.5

Former Oklahoma QB and assistant Josh Heupel returns to Norman as the Volunteers’ head coach on Saturday night. UT QB Nico Iamaleava has become an early Heisman favorite with his play so far, and that high-powered offense will put the pressure on Oklahoma QB Jackson Arnold to get things going in the passing game.

Live9 updates

  • The best game of the early slate is an ACC showdown between NC State and Clemson, so we’ll be following that for the most part. But we’ll be giving updates from across the country throughout the day.

  • No. 24 Illinois stuns No. 22 Nebraska in overtime, off to first 4-0 start since 2011

    Click the photo above to read the story.  (Steven Branscombe/Getty Images)

    Click the photo above to read the story. (Steven Branscombe/Getty Images)

  • What to watch: Week 4 college football viewing guide

    Will we see a major upset in Week 4? (Taylar Seivert/Yahoo Sports)Will we see a major upset in Week 4? (Taylar Seivert/Yahoo Sports)

    Will we see a major upset in Week 4? (Taylar Seivert/Yahoo Sports)

  • How is Travis Hunter not the Heisman Trophy favorite?

    Click the photo above to read the story. (Andrew Wevers/Getty Images)Click the photo above to read the story. (Andrew Wevers/Getty Images)

    Click the photo above to read the story. (Andrew Wevers/Getty Images)

  • Arkansas AD says school needs $12 million more per year in NIL donations to be competitive

    Click the photo above to read the story. (Wesley Hitt/Getty Images)Click the photo above to read the story. (Wesley Hitt/Getty Images)

    Click the photo above to read the story. (Wesley Hitt/Getty Images)

  • Here’s what the 12-team bracket looks like after Week 3

    Here's what the CFP picture looks like.Here's what the CFP picture looks like.

    Here’s what the CFP picture looks like.

  • No, Arch Manning isn’t a serious Heisman contender despite what his odds suggest

    Who's in the Heisman conversation after Week 3 of the college football season? (Taylar Seivert/Yahoo Sports)Who's in the Heisman conversation after Week 3 of the college football season? (Taylar Seivert/Yahoo Sports)

    Who’s in the Heisman conversation after Week 3 of the college football season? (Taylar Seivert/Yahoo Sports)

  • The next wave of realignment is in Memphis’ hands

    Click the photo above to read the story. (Chris McDill/Getty Images)Click the photo above to read the story. (Chris McDill/Getty Images)

    Click the photo above to read the story. (Chris McDill/Getty Images)

  • Good morning folks and welcome to our Week 4 college football live tracker! We’ll be delivering play-by-play and highlights throughout the day on what should be an action-packed Saturday.

    The first games kick off in about 30 minutes. In the meantime, read up on everything that’s going on.

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