The 49ers will have running back Isaac Guerendo for Monday Night Football.
Guerendo, who missed last week’s game with a hamstring injury, does not have an injury designation for the game against the Lions. Patrick Taylor Jr. started in his place against the Dolphins.
The 49ers have running backs Christian McCaffrey (knee), Elijah Mitchell (hamstring) and Jordan Mason (ankle) on injured reserve, which elevated Guerendo to the starting role Dec. 8.
The team ruled out offensive guard Spencer Burford (calf), offensive guard Aaron Banks (knee), defensive end Robert Beal (ankle) and linebacker Dre Greenlaw (calf) for Monday night.
The 49ers list cornerback Charvarius Ward (personal), safety Ji’Ayir Brown (ankle), offensive tackle Colton McKivitz (knee) and linebacker Tatum Bethune (knee) as questionable.
