Duke vs. Kansas prediction: College basketball odds, picks, best bets Tuesday

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Does anyone have love for the Kansas Jayhawks?

The country’s No. 1 men’s college basketball squad is a 2.5-point underdog on a neutral court to No. 11 Duke on Tuesday night.

Both teams should be at full strength as we head into the marquee affair in Las Vegas.

KenPom, the gold standard college basketball analytical site, rates Duke as a four-point favorite in this neutral-court matchup.

It also has Duke ranked fourth and Kansas at No. 9.

It could be wise, though, to go against the grain in this one as money begins to come in on Kansas as we get closer to game time.

Duke vs. Kansas odds

Team Spread Moneyline Total
Duke -2.5 (-110) -150 Over 149.5 (-110)
Kansas +2.5 (-110) +125 Under 149.5 (-110)
Odds provided by BetMGM

Duke vs. Kansas prediction

We all know that Cooper Flagg will be a major piece of the offensive puzzle for Duke, as he’s been the clear Wooden Award favorite in the early going.

Flagg impressively put together a 24-point, six-rebound, three-assist game in a dominant 14-point victory over No. 22 Arizona last Friday.

He’s largely considered among the best college basketball players in the country and is expected to be among the first players — if not No. 1 — selected in the 2025 NBA Draft.


Hunter Dickinson leads No. 1 Kansas. Tyler McFarland/Getty Images

Where things get a little shaky for the Blue Devils is their size down low, as center Khaman Maluach is the only one receiving true minutes so far.

Kansas’ 24-year-old big man Hunter Dickinson is still leading things for the Jayhawks as a dominant presence down low both on the glass and on defense.

His rim protection is critical to the Kansas game plan. He’s averaging 1.8 blocks per game and a double-double on top of that.


Cooper Flagg is an elite college hoops prospect and has looked excellent in the early going.
Cooper Flagg is an elite college hoops prospect and has looked excellent in the early going. AP

Betting on College Basketball?


Anchored by Dickinson and strong guard play featuring Zeke Mayo and AJ Storr, Kansas is very live to pull the upset on a neutral court.

Odds say this will be an upset even if the rankings don’t, but put a wager on Kansas’ moneyline.

If the Jayhawks can stay out of foul trouble, they should be the more well-rounded squad Tuesday night.

PICK: Kansas moneyline (+130, DraftKings)


Why Trust New York Post Betting

Erich Richter is a brazilian jiu-jitsu blue belt but he has a black belt in MMA betting. During the football season he’s showcased massive profits at The Post in the player prop market the last two seasons. While constantly betting long shots, his return on investment is 30.15 percent since 2022.

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